There are a number of good Tank Heartrunes for PvE Tanks in New World.
The things you need to consider when choosing a Heartrune include how experienced you are at Tanking, how good is the group you are doing the content with, and do you have an experienced healer? These things can all effect which Heartrune will be the most useful.
To unlock the Heartrune Gem slot you will need to progress through the Brimstone Sands main quest until you can do ‘The Antiquarian’s Dream’ side quest which allows you access to the ‘Secrets of the Heartgem’ quest.
To obtain Heartrunes you’ll need to complete Expeditions.
You are rewarded with a Minor Heartrune of Cannon Blast for completing the introductory quest and additional can be obtain from Barnacles & Black Powder. Minor Heartrune of Grasping Vines drop from the last boss in the Garden of Genesis, Minor Heartrune of Stoneform drops from the last boss of Lazarus, Minor Heartrune of Detonate drops from the last boss of Ennead and Minor Heartrune of Dark Ascent is dropped by the last boss of Tempest’s Heart.
Once you obtain a basic Heartrune you can upgrade them and select specific upgraded Heartrunes with the perks you want by making sure you have them in your inventory and then visit a Stonecutting station.
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